The Effect of a Dietary Supplement Rich in Nitric Oxide in Patients Diagnosed With Primary Ciliary Dyskinesia.
The purpose of this study is to determine the effect of a dietary supplement rich in nitric oxide (NO) on nasal nitric oxide and fractional exhaled nitric oxide (FeNO),on ciliary beat frequency assessed by high-speed digital video microscopy and on lung function assessed by spirometry in normal patients and patients with Primary ciliary dyskinesia (PCD).
- Primary Ciliary Dyskinesia
- Eligible Ages
- Between 4 Years and 99 Years
- Eligible Genders
- Accepts Healthy Volunteers
Experimental group: - PCD patients Control Group: - patients with no known chronic lung disease - 18 years to 99 years
(both PCD patients and control group): - any other pulmonary co-morbidities and diseases entities like cystic fibrosis, nasal sinus surgery, nasal sinus hypoplasia/aplasia, deviated nasal septum, nasal polyps and with upper respiratory tract infection - patients allergic to beet - a known prolonged bleeding disorder.
- Study Type
- Intervention Model
- Parallel Assignment
- Primary Purpose
- None (Open Label)
- The University of Texas Health Science Center, Houston
Study ContactRicardo A Mosquera, MD