Self Transcranial Direct Current Stimulation and Mindfulness-based Meditation for Pain in Older Adults With Knee Osteoarthritis
Purpose
The purpose of this study is to determine the feasibility and preliminary efficacy of a two-week self tDCS and mindfulness-based meditation for pain in older adults with knee osteoarthritis (OA).
Condition
- Knee Osteoarthritis
Eligibility
- Eligible Ages
- Between 50 Years and 85 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- self-reported unilateral or bilateral knee OA pain, according to American College of Rheumatology criteria. According to American College of Rheumatology criteria, participants should meet at least 3 of 6 criteria, including age > 50 years, stiffness < 30 minutes, crepitus, bony tenderness, bony enlargement, and no palpable warmth. - have had knee OA pain in the past 3 months with an average of at least 30 on a 100 Numeric Rating Scale (NRS) for pain - can speak and read English - have a device with internet access that can be used for secure video conferencing for real-time remote supervision - have no plan to change medication regimens for pain throughout the trial - are able to travel to the coordinating center - are willing and able to provide written informed consent prior to enrollment
Exclusion Criteria
- Participants will be excluded if they have concurrent medical conditions that hinder the completion of the protocol, including any of the following - history of brain surgery, brain tumor, seizure, stroke, or intracranial metal implantation - serious medical illness, such as uncontrolled hypertension (i.e., systolic blood pressure/ diastolic blood pressure ≥ 150/95 mm Hg), heart failure, or history of acute myocardial infarction - alcohol/substance abuse - cognitive impairment - pregnancy or lactation - hospitalization within the preceding year for psychiatric illness
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel Assignment
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Outcomes Assessor)
Arm Groups
Arm | Description | Assigned Intervention |
---|---|---|
Experimental tDCS with mindfulness-based meditation |
Self Transcranial Direct Current Stimulation (tDCS) with Mindfulness-Based Meditation |
|
Sham Comparator sham tDCS with sham meditation |
Sham self Transcranial Direct Current Stimulation (tDCS) with sham Meditation |
|
More Details
- Status
- Completed
- Sponsor
- The University of Texas Health Science Center, Houston