CompARing Long terM Outcomes in Chronic Stroke Survivors Across Investigational Assessments Following a Prescribed Upper Extremity Exercise Program

Purpose

The purpose of the study is to compare assessments of arm function following a standard exercise program in chronic stroke patients.

Condition

  • Chronic Stroke

Eligibility

Eligible Ages
Between 18 Years and 80 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Single qualifying stroke event as confirmed by CT or MRI - At least 1 month post stroke - Score of at least 2-/5 on Manual Muscle Test for wrist flexors or extensors, indicating adequate movement to complete robotic device use - Able to follow written instructions

Exclusion Criteria

  • Prior arm injury impacting available passive or active range of motion or significant arm pain with movement - Underlying brain pathologies such as metastatic or primary brain malignancies, comorbid multiple sclerosis, etc. - Prior significant drug or alcohol abuse - Diagnosed with dementia - Pre-stroke baseline modified Rankin Scale (mRS) >3 - History of seizure/epilepsy - History of clinically significant ischemic or hemorrhagic stroke prior to index stroke resulting in prior arm injury or weakness. - Pregnancy - Contraindication to MRI or Transcranial Magnetic Stimulation (TMS). - Medical instability assessed by the treating stroke physician to participate to the study.

Study Design

Phase
N/A
Study Type
Interventional
Allocation
N/A
Intervention Model
Single Group Assignment
Primary Purpose
Treatment
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
ARM-program
  • Other: Standard Occupational Therapy Arm Exercise Program
    Standard exercise program will be provided addressing shoulder, elbow, forearm, wrist, and hand with expectation that participant will complete 3 times a week. Exercise program will be updated at assessment timepoints as needed with change in arm function.
    Other names:
    • standard occupational therapy arm exercises

Recruiting Locations

The University of Texas Health Science Center at Houston
Houston, Texas 77030
Contact:
Sean Savitz, MD
713-500-7083
Sean.I.Savitz@uth.tmc.edu

More Details

Status
Recruiting
Sponsor
The University of Texas Health Science Center, Houston

Study Contact

Sean Savitz, MD
(713) 500-7083
Sean.I.Savitz@uth.tmc.edu