Home-based tDCS and Mindfulness-based Meditation for Self-management of Clinical Pain and Symptoms
Purpose
The purpose of this study is to determine the effects of active transcranial direct current stimulation (tDCS) paired with active mindfulness-based meditation (MBM) on clinical pain,osteo arthritis (OA)-related clinical symptoms, physiopsychological pain processing and participant satisfaction with treatment in patients with knee OA.
Condition
- Osteo Arthritis Knee
Eligibility
- Eligible Ages
- Between 50 Years and 85 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- have symptomatic knee OA based on American College of Rheumatology clinical criteria - have had knee OA pain in the past 3 months with an average of at least 30 on a 0-100 NRS for pain, - can speak and read English - have no plan to change medication regimens for pain throughout the trial
Exclusion Criteria
- history of brain surgery, brain tumor, seizure, stroke, or intracranial metal implantation - systemic rheumatic disorders, including rheumatoid arthritis,systemic lupus erythematosus, and fibromyalgia - alcohol/substance abuse - diminished cognitive function that would interfere with understanding study procedures (i.e., Mini-Mental Status Exam score ≤ 23) - pregnancy or lactation - prosthetic knee replacement or non-arthroscopic surgery to the affected knee - hospitalization within the preceding year for psychiatric illness - no access to a device that can be used for secure videoconferencing for real-time remote supervision.
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel Assignment
- Primary Purpose
- Treatment
- Masking
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Arm Groups
Arm | Description | Assigned Intervention |
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Experimental active tDCS paired with active MBM, |
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Active Comparator sham tDCS paired with active MBM |
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Active Comparator active tDCS paired with sham MBM |
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Sham Comparator sham tDCS paired with sham MBM |
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Recruiting Locations
More Details
- Status
- Recruiting
- Sponsor
- University of Arizona