Does Blood Flow Restriction Training Improve Quadriceps Function After Arthroscopic Knee Surgery?
Purpose
The purpose of this study is to evaluate the effectiveness of physical therapy (PT) plus BFR training compared to PT alone (without BFR training) after ACL reconstruction in patients who require extended limited weight bearing through assessment of patient reported outcomes and functional testing. The hypothesis is that PT plus BFR training will mitigate the loss of quadriceps muscle cross-sectional area, strength, and function while also improving early clinical and functional results.
Conditions
- Quadriceps Atrophy
- ACL Reconstruction
Eligibility
- Eligible Ages
- Between 14 Years and 55 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Anterior cruciate ligament (ACL) reconstruction with concomitant meniscus or cartilage restoration procedures - Adherence to modified weight bearing status before initiation of PT - Expected participation in recreational or competitive sports after release to full activities
Exclusion Criteria
- Unable to attend (or participate in) physical therapy - Pregnancy - Malignancy - Fracture - Peripheral vascular disease - History of deep vein thrombosis (DVT)
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel Assignment
- Primary Purpose
- Treatment
- Masking
- None (Open Label)
- Masking Description
- Blinding is not possible given the nature of the intervention.
Arm Groups
Arm | Description | Assigned Intervention |
---|---|---|
Experimental Physical therapy (PT) plus blood flow restriction (BFR) |
Physical therapy consists of two or three 90-minute sessions per week for 6 weeks and a minimum of 18 visits required for study inclusion. With BFR, exercises will be performed at 30% one-rep max with the BFR cuff placed around the proximal thigh and inflated to 80% of limb occlusion pressure (avg: 150 mmHg). |
|
Active Comparator Physical therapy |
Physical therapy consists of two or three 90-minute sessions per week for 6 weeks and a minimum of 18 visits required for study inclusion. |
|
Recruiting Locations
The University of Texas Health Science Center at Houston
Houston, Texas 77030
Houston, Texas 77030
More Details
- Status
- Recruiting
- Sponsor
- The University of Texas Health Science Center, Houston