Cortical Plasticity in Spastic Diplegia After Selective Dorsal Rhizotomy
Purpose
The purpose of this study is to characterize the cortical connectivity changes in the brain of spastic diplegic children after Selective Dorsal Rhizotomy.
Condition
- Spastic Diplegia
Eligibility
- Eligible Ages
- Between 3 Years and 18 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Children diagnosis with Spastic Diplegia and having Selective Dorsal Rhizotomy surgery
Exclusion Criteria
- No Selective Dorsal Rhizotomy surgery
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- N/A
- Intervention Model
- Single Group Assignment
- Primary Purpose
- Diagnostic
- Masking
- None (Open Label)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Other 3Tesla MRI with DTI-MRI and rsfcMRI |
Patients will receive 2 post-operative MRI's with DTI and rsfcMRI at 2 months and 12 months. |
|
Recruiting Locations
UTHealth & Children's Memorial Hermann Hospital
Houston, Texas 77030
Houston, Texas 77030
More Details
- Status
- Recruiting
- Sponsor
- The University of Texas Health Science Center, Houston
Detailed Description
To establish the structural changes in the corticopyramidal tract using diffusion tractography imaging (DTI) due to selective dorsal rhizotomy and compare the resting state functional connectivity(rsfcMRI) temporal latency differences of spastic diplegics for Selective Dorsal Rhizotomy.